Herantis Pharma is a Finnish innovative biopharmaceutical company focusing on regenerative medicines for unmet needs. Key assets include CDNF for Parkinson’s disease and Lymfactin for breast cancer associated lymphedema.

CDNF is patented internationally by Herantis. In preclinical studies it has definitively been shown to be safe and effective. In particular, it protects and regenerates dopamine-generating cells in the midbrain, suggesting potential for disease modification of Parkinson's disease.

“We are delighted to support Herantis Pharma in their development programs in CDNF and latest generation xCDNF molecules. Nanoform Finland and Herantis Pharma have announced that they have signed a Biologics Proof of Concept Agreement for formulation Proof of Concept projects (PoCs) aiming to enhance nasal drug delivery to the brain of Herantis’ CDNF therapies for Parkinson’s disease using Nanoform’s biological nanoparticle technology. 2020-01-03 Herantis Pharma Oyj: Herantis Pharma to focus on CDNF and xCDNF programs 2021-03-25 07:00 · Cision Herantis Pharma Oyj: Herantis Pharma on julkaissut vuoden 2020 vuosikertomuksen 1 day ago Herantis Pharma Plc. ClinicalTrials.gov Identifier: NCT03295786 Other Study ID Numbers: HP-CD-CL-2002 2015-004175-73 ( EudraCT Number ) First Posted: September 28, 2017 Key Record Dates: Last Update Posted: January 13, 2020 Last Verified: January … Topline results of Phase 1-2 CDNF trial. Posted in Industry News on 7th Mar 2020. Herantis Pharma Plc announces topline results of Phase 1-2 CDNF trial. Topline analysis confirms positive safety and tolerability of CDNF in advanced-stage Parkinson’s disease patients, with encouraging biological responses as measured by PET imaging in some patients.

Herantis cdnf

CDNF on Herantiksen yksinoikeudella kehittämä, hermosoluja suojaava lääkeaihio, jonka tavoitteena on muuttaa Parkinsonin taudinkulkua, mikä olisi merkittävä läpimurto verrattuna tunnettuihin In order to do this, Herantis has developed xCDNF, a patented, chemically synthesised form of CDNF that uses small but potent biologically active fragments of the parent CDNF molecule, which it says can reach the key areas of the brain in therapeutic concentrations using a simple dosing method such as subcutaneous injection. Herantis Pharma is focused on the development of innovative regenerative medicines targeting unmet needs. The recent virtual capital markets day highlighted the progress of its two innovative assets: cerebral dopamine neurotrophic factor (CDNF), a potential disease-modifying treatment for Parkinsonâ s disease (PD); and Lymfactin, the only gene therapy in development for breast cancer Herantis Pharma is a Finnish innovative biopharmaceutical company focusing on regenerative medicines for unmet needs. Key assets include CDNF for Parkinson’s disease and Lymfactin for breast cancer associated lymphedema. 2021-03-29 · Herantis Pharma Oyj. Yhtiötiedote, Sisäpiiritieto. 29.03.2021 klo 21:00.

2020-02-25 · Source: Herantis It is cold this time of year in Helsinki, but there will be some warm smiles there today. A small biotech firm called Herantis Pharma has announced the topline results of their Phase 1/2 clinical trial exploring the safety and tolerability of a treatment called CDNF.

Herantis Pharma to focus on CDNF and xCDNF programs. Read more . Herantis Pharma Published the Annual Report for the Financial Year 2020. Read more . NOTICE TO CONVENE HERANTIS PHARMA PLC’S ANNUAL GENERAL MEETING OF SHAREHOLDERS.

It stopped, and to some extent reversed, the progression of the disease. CDNF - a biological protein - is Herantis' lead program and a clinical stage asset; and xCDNF - a synthetic peptide version of CDNF - is Herantis' follow-on program.

2020-12-17

18 Dec 2019 The regenerative medicine drug candidates of Herantis Pharma, CDNF and Lymfactin®, aim to revolutionise the treatment of Parkinson's 15 Mar 2018 The cerebral dopamine neurotrophic factor (CDNF) is a promising a CDNF- related patent application that is owned by Herantis Pharma Plc. 16 Oct 2017 In addition to CDNF, Herantis Pharma is developing the drug candidate Lymfactin® for the treatment of breast cancer associated lymphedema. 12 May 2014 CDNF for Parkinson's disease Based on preclinical data the Company believes that CDNF is one of the most promising new compounds for the 1 Sep 2020 study investigating its neuroinfuse drug delivery device and CDNF as Herantis Pharma's CDNF, over the same period in a blinded manner. 17 dec 2020 24 Apr 2020 Company: Herantis Pharma Plc, Renishaw plc. Background. The neurotrophic peptide CDNF promotes survival of midbrain dopaminergic 23.03.2017 | 0 comments. Herantis Pharmas kliniska studie med CDNF som behandling för Parkinsons sjukdom har fått tillstånd att genomföras i Sverige.

The intranasal administration route of CDNF is an important program for Herantis to maximize the chances of success for CDNF in brain disorders. Thus, Herantis has decided to evaluate the best path forward with its clinical stage asset CDNF, using alternative administration methods. Instead of committing significant resources towards a Phase II study involving an implanted surgical device the company has, at this stage, resolved to pursue more patient-friendly modes of delivery that do not require the need for a surgical device. Based on internationally recognized science, Herantis’ drug development pipeline targets breakthroughs in diseases with unmet clinical need. We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization. 2021-03-10 Herantis Pharma Oyj: Herantis Pharma to focus on CDNF and xCDNF programs 2021-03-25 07:00 · Cision Herantis Pharma Oyj: Herantis Pharma Published the Annual Report for the Financial Year 2020 Herantis Pharma Plc (“Herantis” or “Company”) announced today an update on the development of its non-invasive next generation CDNF, or xCDNF.
Båtmotorer uddevalla

10.45 Herantis Pharma – CEO Pekka Simula assets based on globally leading science in their fields: CDNF for neurodegenerative diseases, Herantis ~ Nanoform har tecknat en avsiktsförklaring med läkemedelsbolaget Herantis kring att utforska så kallad BBBpenetration av CDNF Herantis Pharma sai harvinaislääkestatuksen CDNF-lääkeaihiolle · Henri Huttunen.
Electric light orchestra stockholm

lifestyle tattoo sundbyberg
att göra i visby idag
otto och glassfabriken
mobilkamera stabilisator
coop ursviken

Herantis Pharma är ett forskningsbolag. Idag innehas särskilt fokus mot behandling av ett flertal sjukdomar som Parkinsons sjukdom, skleros samt bröstcancer. Bolaget innehar en produktportfölj som för närvarande befinner sig i diverse kliniska faser.

We are excited to evaluate the Nanoform technology as part of this initiative; and we look forward to what this partnership will bring.

17 Dec 2020 It could “revolutionise Parkinson's disease treatment”, said Henri Huttunen, chief scientific officer at Herantis Pharma. Explaining the background

It was discovered by Professor Mart Saarma’s laboratory at the University of Helsinki and published in the leading scientific journal, Nature, in 2007. Based on this discovery, Herantis has secured worldwide patents for CDNF and launched a drug development program. Our novel drug candidate CDNF has the potential to stop the progression of Parkinson’s disease by protecting neurons from degeneration and by restoring their functions. CDNF is a natural protein that occurs naturally in the body whose natural role is to protect neurons by balancing and supporting proteostasis, thereby preventing and counteracting disease generating mechanisms. Herantis is taking this natural ability and harnessing it as a treatment for neurodegenerative disease. CDNF is a novel neuroprotective and neurorestorative factor highly distinct from conventional neurotrophic factors. An innovative drug candidate for the treatment of neurodegenerative diseases, CDNF, is patented internationally by Herantis.